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==Crystal Structure of Multi-drug Resistant HIV-1 Protease PR-S17 in Complex with Darunavir==
==Crystal Structure of Multi-drug Resistant HIV-1 Protease PR-S17 in Complex with Darunavir==
<StructureSection load='5t2z' size='340' side='right' caption='[[5t2z]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='5t2z' size='340' side='right'caption='[[5t2z]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5t2z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T2Z FirstGlance]. <br>
<table><tr><td colspan='2'>[[5t2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T2Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t2e|5t2e]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2z OCA], [http://pdbe.org/5t2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t2z RCSB], [http://www.ebi.ac.uk/pdbsum/5t2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t2z OCA], [https://pdbe.org/5t2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t2z RCSB], [https://www.ebi.ac.uk/pdbsum/5t2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t2z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/I7BFC3_9HIV1 I7BFC3_9HIV1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5t2z" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5t2z" style="background-color:#fffaf0;"></div>
==See Also==
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Agniswamy, J]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Weber, I T]]
[[Category: Large Structures]]
[[Category: Hydrolase]]
[[Category: Agniswamy J]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Weber IT]]
[[Category: Inhibitor]]
[[Category: Protease]]
Retrieved from "https://proteopedia.org/5t2z"