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==Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by valine==
==Mutant ribosomal protein l1 from thermus thermophilus with threonine 217 replaced by valine==
<StructureSection load='4reo' size='340' side='right' caption='[[4reo]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='4reo' size='340' side='right'caption='[[4reo]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4reo]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3u42 3u42]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4REO FirstGlance]. <br>
<table><tr><td colspan='2'>[[4reo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3u42 3u42]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4REO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4REO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ad2|1ad2]], [[3tg8|3tg8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4reo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4reo OCA], [http://pdbe.org/4reo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4reo RCSB], [http://www.ebi.ac.uk/pdbsum/4reo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4reo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4reo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4reo OCA], [https://pdbe.org/4reo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4reo RCSB], [https://www.ebi.ac.uk/pdbsum/4reo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4reo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RL1_THETH RL1_THETH]] The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.[HAMAP-Rule:MF_01318]  Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318]  
[https://www.uniprot.org/uniprot/RL1_THETH RL1_THETH] The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.[HAMAP-Rule:MF_01318]  Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Gabdulkhakov, A G]]
[[Category: Large Structures]]
[[Category: Nevskaya, N A]]
[[Category: Thermus thermophilus]]
[[Category: Nikonov, S V]]
[[Category: Gabdulkhakov AG]]
[[Category: Tishchenko, S V]]
[[Category: Nevskaya NA]]
[[Category: Ribosomal protein]]
[[Category: Nikonov SV]]
[[Category: Rna binding protein]]
[[Category: Tishchenko SV]]
[[Category: Rossmann fold]]