2jab: Difference between revisions
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==A designed ankyrin repeat protein evolved to picomolar affinity to Her2== | ==A designed ankyrin repeat protein evolved to picomolar affinity to Her2== | ||
<StructureSection load='2jab' size='340' side='right' caption='[[2jab]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2jab' size='340' side='right'caption='[[2jab]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jab]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAB OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2jab]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAB FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jab OCA], [https://pdbe.org/2jab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jab RCSB], [https://www.ebi.ac.uk/pdbsum/2jab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jab ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jab_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jab_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Joos | [[Category: Large Structures]] | ||
[[Category: Lawrence | [[Category: Synthetic construct]] | ||
[[Category: McKern | [[Category: Joos TO]] | ||
[[Category: Pecorari | [[Category: Lawrence MC]] | ||
[[Category: Pluckthun | [[Category: McKern NM]] | ||
[[Category: Schwenk | [[Category: Pecorari F]] | ||
[[Category: Steiner | [[Category: Pluckthun A]] | ||
[[Category: Ward | [[Category: Schwenk JM]] | ||
[[Category: Wyler | [[Category: Steiner D]] | ||
[[Category: Zahnd | [[Category: Ward CW]] | ||
[[Category: Wyler E]] | |||
[[Category: Zahnd C]] | |||
