5uqe: Difference between revisions
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New page: '''Unreleased structure''' The entry 5uqe is ON HOLD Authors: Pascoal, C.C., Dias, S.M.G., Ambrosio, A.L.B. Description: Multidomain structure of human kidney-type glutaminase(KGA/GLS)... |
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==Multidomain structure of human kidney-type glutaminase(KGA/GLS)== | |||
<StructureSection load='5uqe' size='340' side='right'caption='[[5uqe]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5uqe]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UQE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=04A:N,N-[SULFANEDIYLBIS(ETHANE-2,1-DIYL-1,3,4-THIADIAZOLE-5,2-DIYL)]BIS(2-PHENYLACETAMIDE)'>04A</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqe OCA], [https://pdbe.org/5uqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uqe RCSB], [https://www.ebi.ac.uk/pdbsum/5uqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqe ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | |||
==See Also== | |||
*[[Glutaminase 3D structures|Glutaminase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Ambrosio | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ambrosio ALB]] | ||
[[Category: Dias SMG]] | |||
[[Category: Pasquali CC]] | |||