5uqu: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
m Protected "5uqu" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 5uqu is ON HOLD  until Paper Publication
==Crystal structure of mutant 2-methylcitrate synthase (mcsAG352A) from Aspergillus fumigatus==
<StructureSection load='5uqu' size='340' side='right'caption='[[5uqu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5uqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus Aspergillus fumigatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UQU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uqu OCA], [https://pdbe.org/5uqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uqu RCSB], [https://www.ebi.ac.uk/pdbsum/5uqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uqu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRPC_ASPFM PRPC_ASPFM] Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Has also citrate synthase activity using as substrates acetyl-CoA and oxaloacetate. May play a role in virulence.<ref>PMID:16008561</ref>


Authors: Schlachter, C., Chruszcz, M.
==See Also==
 
*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
Description: Crystal structure of mutant 2-methylcitrate synthase (mcsAG352A) from Aspergillus fumigatus
*[[Methylcitrate synthase|Methylcitrate synthase]]
[[Category: Unreleased Structures]]
== References ==
[[Category: Chruszcz, M]]
<references/>
[[Category: Schlachter, C]]
__TOC__
</StructureSection>
[[Category: Aspergillus fumigatus]]
[[Category: Large Structures]]
[[Category: Chruszcz M]]
[[Category: Schlachter C]]
Retrieved from "https://proteopedia.org/5uqu"