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==Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair==
==Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair==
<StructureSection load='4l6p' size='340' side='right' caption='[[4l6p]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
<StructureSection load='4l6p' size='340' side='right'caption='[[4l6p]], [[Resolution|resolution]] 2.68&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4l6p]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L6P FirstGlance]. <br>
<table><tr><td colspan='2'>[[4l6p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L6P FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l60|4l60]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6p OCA], [http://pdbe.org/4l6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l6p RCSB], [http://www.ebi.ac.uk/pdbsum/4l6p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6p OCA], [https://pdbe.org/4l6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l6p RCSB], [https://www.ebi.ac.uk/pdbsum/4l6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST]] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref>
[https://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]]
*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Boehm, E]]
[[Category: Large Structures]]
[[Category: Washington, T]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Dna binding protein]]
[[Category: Boehm E]]
[[Category: Dna mismatch repair]]
[[Category: Washington T]]
[[Category: Dna replication]]
[[Category: Nucleus]]
[[Category: Sumoylation]]
[[Category: Translesion synthesis]]
[[Category: Ubiquitylation]]
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