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==Complex structure of presenilin homologue PSH bound to an inhibitor==
==Complex structure of presenilin homologue PSH bound to an inhibitor==
<StructureSection load='4y6k' size='340' side='right' caption='[[4y6k]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
<StructureSection load='4y6k' size='340' side='right'caption='[[4y6k]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4y6k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y6K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y6K FirstGlance]. <br>
<table><tr><td colspan='2'>[[4y6k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanoculleus_marisnigri_JR1 Methanoculleus marisnigri JR1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y6K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4B5:N-{(2R,4S,5S)-2-BENZYL-5-[(TERT-BUTOXYCARBONYL)AMINO]-4-HYDROXY-6-PHENYLHEXANOYL}-L-LEUCYL-L-PHENYLALANINAMIDE'>4B5</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.855&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y6k OCA], [http://pdbe.org/4y6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y6k RCSB], [http://www.ebi.ac.uk/pdbsum/4y6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y6k ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4B5:N-{(2R,4S,5S)-2-BENZYL-5-[(TERT-BUTOXYCARBONYL)AMINO]-4-HYDROXY-6-PHENYLHEXANOYL}-L-LEUCYL-L-PHENYLALANINAMIDE'>4B5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y6k OCA], [https://pdbe.org/4y6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y6k RCSB], [https://www.ebi.ac.uk/pdbsum/4y6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y6k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A3CWV0_METMJ A3CWV0_METMJ]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dang, S]]
[[Category: Large Structures]]
[[Category: Shi, Y]]
[[Category: Methanoculleus marisnigri JR1]]
[[Category: Wang, J]]
[[Category: Dang S]]
[[Category: Wu, S]]
[[Category: Shi Y]]
[[Category: Complex]]
[[Category: Wang J]]
[[Category: Inhibitor]]
[[Category: Wu S]]
[[Category: Membrane protein-inhibitor complex]]

Latest revision as of 15:34, 8 November 2023

Complex structure of presenilin homologue PSH bound to an inhibitor

4y6k, resolution 3.85Å

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