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==Crystal Structure of Type III pantothenate kinase (PanK III) from Burkholderia cenocepacia complexed with pantothenate, imidodiphosphate, and AMP==
==Crystal Structure of Type III pantothenate kinase (PanK III) from Burkholderia cenocepacia complexed with pantothenate, imidodiphosphate, and AMP==
<StructureSection load='5b8h' size='340' side='right' caption='[[5b8h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5b8h' size='340' side='right'caption='[[5b8h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5b8h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B8H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B8H FirstGlance]. <br>
<table><tr><td colspan='2'>[[5b8h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_cenocepacia_J2315 Burkholderia cenocepacia J2315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B8H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PN:IMIDODIPHOSPHORIC+ACID'>2PN</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1999&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PN:IMIDODIPHOSPHORIC+ACID'>2PN</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b8h OCA], [https://pdbe.org/5b8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b8h RCSB], [https://www.ebi.ac.uk/pdbsum/5b8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b8h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b8h OCA], [http://pdbe.org/5b8h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b8h RCSB], [http://www.ebi.ac.uk/pdbsum/5b8h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b8h ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAX_BURCJ COAX_BURCJ]] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.  
[https://www.uniprot.org/uniprot/COAX_BURCJ COAX_BURCJ] Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
==See Also==
*[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pantothenate kinase]]
[[Category: Burkholderia cenocepacia J2315]]
[[Category: Structural genomic]]
[[Category: Large Structures]]
[[Category: Burkholderia cenocepacia]]
[[Category: Coa biosynthesis]]
[[Category: Coax]]
[[Category: Ssgcid]]
[[Category: Transferase]]
[[Category: Type iii pantothenate kinase]]