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==Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution==
==Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution==
<StructureSection load='4tv7' size='340' side='right' caption='[[4tv7]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4tv7' size='340' side='right'caption='[[4tv7]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4tv7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TV7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4tv7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TV7 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tv7 OCA], [http://pdbe.org/4tv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tv7 RCSB], [http://www.ebi.ac.uk/pdbsum/4tv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tv7 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tv7 OCA], [https://pdbe.org/4tv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tv7 RCSB], [https://www.ebi.ac.uk/pdbsum/4tv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tv7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU]] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref>
[https://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4tv7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4tv7" style="background-color:#fffaf0;"></div>
==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Goto, M]]
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Okuda, K]]
[[Category: Large Structures]]
[[Category: Yoshimura, T]]
[[Category: Goto M]]
[[Category: Transcription]]
[[Category: Okuda K]]
[[Category: Transcriptional regulator]]
[[Category: Yoshimura T]]