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[[Image:1tuz.gif|left|200px]]


{{Structure
==NMR Structure of the Diacylglycerol kinase alpha, NESGC target HR532==
|PDB= 1tuz |SIZE=350|CAPTION= <scene name='initialview01'>1tuz</scene>
<StructureSection load='1tuz' size='340' side='right'caption='[[1tuz]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1tuz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TUZ FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= DAGK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tuz OCA], [https://pdbe.org/1tuz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tuz RCSB], [https://www.ebi.ac.uk/pdbsum/1tuz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tuz ProSAT], [https://www.topsan.org/Proteins/NESGC/1tuz TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tuz OCA], [http://www.ebi.ac.uk/pdbsum/1tuz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tuz RCSB]</span>
[https://www.uniprot.org/uniprot/DGKA_HUMAN DGKA_HUMAN] Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tu/1tuz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tuz ConSurf].
<div style="clear:both"></div>


'''NMR Structure of the Diacylglycerol kinase alpha, NESGC target HR532'''
==See Also==
 
*[[Diacylglycerol kinase 3D structures|Diacylglycerol kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1TUZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TUZ OCA].
[[Category: Diacylglycerol kinase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Acton, T.]]
[[Category: Acton T]]
[[Category: Liu, G.]]
[[Category: Liu G]]
[[Category: Montelione, G T.]]
[[Category: Montelione GT]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Shao Y]]
[[Category: Shao, Y.]]
[[Category: Szyperski T]]
[[Category: Szyperski, T.]]
[[Category: Xiao R]]
[[Category: Xiao, R.]]
[[Category: hr532]]
[[Category: kinase]]
[[Category: nesgc]]
[[Category: northeast structural genomics consortium]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:01:25 2008''

Latest revision as of 08:44, 1 May 2024

NMR Structure of the Diacylglycerol kinase alpha, NESGC target HR532

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