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==Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor==
==Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor==
<StructureSection load='5utn' size='340' side='right' caption='[[5utn]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5utn' size='340' side='right'caption='[[5utn]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5utn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UTN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UTN FirstGlance]. <br>
<table><tr><td colspan='2'>[[5utn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UTN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8MA:4-{[6-(CYCLOHEXYLMETHYL)PYRIDINE-2-CARBONYL]AMINO}-3-[(4-FLUOROPHENYL)AMINO]BENZOIC+ACID'>8MA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5utn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5utn OCA], [http://pdbe.org/5utn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5utn RCSB], [http://www.ebi.ac.uk/pdbsum/5utn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5utn ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8MA:4-{[6-(CYCLOHEXYLMETHYL)PYRIDINE-2-CARBONYL]AMINO}-3-[(4-FLUOROPHENYL)AMINO]BENZOIC+ACID'>8MA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5utn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5utn OCA], [https://pdbe.org/5utn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5utn RCSB], [https://www.ebi.ac.uk/pdbsum/5utn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5utn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O40922_HHV8 O40922_HHV8]
==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acker, T M]]
[[Category: Human gammaherpesvirus 8]]
[[Category: Bohn, M F]]
[[Category: Large Structures]]
[[Category: Craik, C S]]
[[Category: Acker TM]]
[[Category: Gable, J]]
[[Category: Bohn M-F]]
[[Category: Capsid maturation]]
[[Category: Craik CS]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Gable J]]
[[Category: Serine hydrolase]]
[[Category: Viral protein]]

Latest revision as of 14:09, 13 March 2024

Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor

5utn, resolution 1.80Å

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