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[[Image:1tyn.jpg|left|200px]]


{{Structure
==ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS==
|PDB= 1tyn |SIZE=350|CAPTION= <scene name='initialview01'>1tyn</scene>, resolution 2.0&Aring;
<StructureSection load='1tyn' size='340' side='right'caption='[[1tyn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CTA:CYCLOTHEONAMIDE+A'>CTA</scene>
<table><tr><td colspan='2'>[[1tyn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TYN FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTA:CYCLOTHEONAMIDE+A'>CTA</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tyn OCA], [https://pdbe.org/1tyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tyn RCSB], [https://www.ebi.ac.uk/pdbsum/1tyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tyn ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tyn OCA], [http://www.ebi.ac.uk/pdbsum/1tyn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tyn RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ty/1tyn_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tyn ConSurf].
<div style="clear:both"></div>


'''ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS'''
==See Also==
 
*[[Trypsin 3D structures|Trypsin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1TYN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYN OCA].
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Albers, M W.]]
[[Category: Albers MW]]
[[Category: Clardy, J.]]
[[Category: Clardy J]]
[[Category: Hagihara, M.]]
[[Category: Hagihara M]]
[[Category: Karmacharya, R.]]
[[Category: Karmacharya R]]
[[Category: Lee, A Y.]]
[[Category: Lee AY]]
[[Category: Schreiber, S L.]]
[[Category: Schreiber SL]]
[[Category: hydrolase(serine protease)]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:02:56 2008''

Latest revision as of 07:30, 30 October 2024

ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS

1tyn, resolution 2.00Å

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