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[[Image:1tz9.jpg|left|200px]]


{{Structure
==Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41==
|PDB= 1tz9 |SIZE=350|CAPTION= <scene name='initialview01'>1tz9</scene>, resolution 2.90&Aring;
<StructureSection load='1tz9' size='340' side='right'caption='[[1tz9]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[1tz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZ9 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
|GENE= uxuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 Enterococcus faecalis])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01261 AP_endonuc_2], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK03906 PRK03906]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz9 OCA], [https://pdbe.org/1tz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1tz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz9 ProSAT], [https://www.topsan.org/Proteins/NESGC/1tz9 TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz9 OCA], [http://www.ebi.ac.uk/pdbsum/1tz9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1tz9 RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/UXUA_ENTFA UXUA_ENTFA] Catalyzes the dehydration of D-mannonate (By similarity).
 
== Evolutionary Conservation ==
'''Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz9_consurf.spt"</scriptWhenChecked>
1TZ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ9 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Enterococcus faecalis]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Mannonate dehydratase]]
  </jmolCheckbox>
[[Category: Single protein]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tz9 ConSurf].
[[Category: Acton, T A.]]
<div style="clear:both"></div>
[[Category: Chen, Y.]]
__TOC__
[[Category: Cooper, B.]]
</StructureSection>
[[Category: Forouhar, F.]]
[[Category: Enterococcus faecalis V583]]
[[Category: Hunt, J F.]]
[[Category: Large Structures]]
[[Category: Montelione, G T.]]
[[Category: Acton TA]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Chen Y]]
[[Category: Shastry, R.]]
[[Category: Cooper B]]
[[Category: Tong, L.]]
[[Category: Forouhar F]]
[[Category: Xiao, R.]]
[[Category: Hunt JF]]
[[Category: alpha-beta protein]]
[[Category: Montelione GT]]
[[Category: nesg]]
[[Category: Shastry R]]
[[Category: northeast structural genomics consortium]]
[[Category: Tong L]]
[[Category: protein structure initiative]]
[[Category: Xiao R]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:03:11 2008''

Latest revision as of 07:30, 30 October 2024

Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41

1tz9, resolution 2.90Å

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