1u4g: Difference between revisions

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[[Image:1u4g.gif|left|200px]]


{{Structure
==Elastase of Pseudomonas aeruginosa with an inhibitor==
|PDB= 1u4g |SIZE=350|CAPTION= <scene name='initialview01'>1u4g</scene>, resolution 1.40&Aring;
<StructureSection load='1u4g' size='340' side='right'caption='[[1u4g]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HPI:N-(1-CARBOXY-3-PHENYLPROPYL)PHENYLALANYL-ALPHA-ASPARAGINE'>HPI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
<table><tr><td colspan='2'>[[1u4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U4G FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pseudolysin Pseudolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.26 3.4.24.26] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HPI:N-(1-CARBOXY-3-PHENYLPROPYL)PHENYLALANYL-ALPHA-ASPARAGINE'>HPI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u4g OCA], [https://pdbe.org/1u4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u4g RCSB], [https://www.ebi.ac.uk/pdbsum/1u4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u4g ProSAT]</span></td></tr>
|RELATEDENTRY=[[1ezm|1EZM]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u4g OCA], [http://www.ebi.ac.uk/pdbsum/1u4g PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1u4g RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/ELAS_PSEAE ELAS_PSEAE] Cleaves elastin, collagen, IgG, and several complement components. Involved in the pathogenesis of P.aeruginosa infections.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u4/1u4g_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u4g ConSurf].
<div style="clear:both"></div>


'''Elastase of Pseudomonas aeruginosa with an inhibitor'''
==See Also==
 
*[[Elastase 3D structures|Elastase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1U4G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U4G OCA].
[[Category: Large Structures]]
[[Category: Pseudolysin]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Single protein]]
[[Category: Bitto E]]
[[Category: Bitto, E.]]
[[Category: McKay DB]]
[[Category: McKay, D B.]]
[[Category: elastase]]
[[Category: inhibition]]
[[Category: peptidase family m4]]
[[Category: x-ray structure]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:05:19 2008''

Latest revision as of 06:38, 23 August 2023

Elastase of Pseudomonas aeruginosa with an inhibitor

1u4g, resolution 1.40Å

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