5v8k: Difference between revisions
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The | ==Homodimeric reaction center of H. modesticaldum== | ||
<StructureSection load='5v8k' size='340' side='right'caption='[[5v8k]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5v8k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Heliomicrobium_modesticaldum Heliomicrobium modesticaldum] and [https://en.wikipedia.org/wiki/Heliomicrobium_modesticaldum_Ice1 Heliomicrobium modesticaldum Ice1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V8K FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C4D:(4E,6E,8E,10E,12E,14E,16E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,4,6,8,10,12,14,16,18,22-decaene'>C4D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGG:1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL'>DGG</scene>, <scene name='pdbligand=GB0:[methyl+9,14-diethyl-4,8,13,18-tetramethyl-20-oxo-3-{3-oxo-3-[(3,7,11-trimethyldodeca-2,6,10-trien-1-yl)oxy]propyl}-3,4,23,25-tetradehydro-24,26-dihydrophorbine-21-carboxylatato(2-)-kappa~4~N~23~,N~24~,N~25~,N~26~]magnesium'>GB0</scene>, <scene name='pdbligand=GBF:[methyl+9,14-diethyl-4,8,13,18-tetramethyl-20-oxo-3-{3-oxo-3-[(3,7,11-trimethyldodeca-2,6,10-trien-1-yl)oxy]propyl}-3,4,23,25-tetradehydro-24,26-dihydrophorbine-21-carboxylatato(2-)-kappa~4~N~23~,N~24~,N~25~,N~26~]magnesium'>GBF</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v8k OCA], [https://pdbe.org/5v8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v8k RCSB], [https://www.ebi.ac.uk/pdbsum/5v8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v8k ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q1MX24_9FIRM Q1MX24_9FIRM] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Reaction centers are pigment-protein complexes that drive photosynthesis by converting light into chemical energy. It is believed that they arose once from a homodimeric protein. The symmetry of a homodimer is broken in heterodimeric reaction center structures, such as those reported previously. The 2.2-A resolution X-ray structure of the homodimeric reaction center/photosystem from the phototroph, Heliobacterium modesticaldum, exhibits perfect C2 symmetry. The core polypeptide dimer and two small subunits coordinate 54 (bacterio)chlorophylls and 2 carotenoids that capture and transfer energy to the electron transfer chain at the center, which performs charge separation and consists of 6 (bacterio)chlorophylls and an iron-sulfur cluster; unlike other reaction centers, it lacks a bound quinone. This structure preserves characteristics of the ancestral reaction center, providing insight into evolution of photosynthesis. | |||
Structure of a symmetric photosynthetic reaction center-photosystem.,Gisriel C, Sarrou I, Ferlez B, Golbeck JH, Redding KE, Fromme R Science. 2017 Jul 27. pii: eaan5611. doi: 10.1126/science.aan5611. PMID:28751471<ref>PMID:28751471</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: Ferlez | <div class="pdbe-citations 5v8k" style="background-color:#fffaf0;"></div> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Heliomicrobium modesticaldum]] | ||
[[Category: Heliomicrobium modesticaldum Ice1]] | |||
[[Category: Large Structures]] | |||
[[Category: Ferlez B]] | |||
[[Category: Fromme R]] | |||
[[Category: Gisriel C]] | |||
[[Category: Golbeck J]] | |||
[[Category: Redding KE]] | |||
[[Category: Sarrou I]] | |||
Latest revision as of 12:37, 13 August 2026
Homodimeric reaction center of H. modesticaldum
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