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==Murin CXCL13 solution structure featuring a folded N-terminal domain==
==Murin CXCL13 solution structure featuring a folded N-terminal domain==
<StructureSection load='5izb' size='340' side='right' caption='[[5izb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='5izb' size='340' side='right'caption='[[5izb]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5izb]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IZB FirstGlance]. <br>
<table><tr><td colspan='2'>[[5izb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IZB FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [http://pdbe.org/5izb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [http://www.ebi.ac.uk/pdbsum/5izb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [https://pdbe.org/5izb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [https://www.ebi.ac.uk/pdbsum/5izb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE]] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.  
[https://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.
 
==See Also==
*[[C-X-C motif chemokine 3D structures|C-X-C motif chemokine 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lortat-Jacob, H]]
[[Category: Large Structures]]
[[Category: Monneau, Y R]]
[[Category: Mus musculus]]
[[Category: Chemokine structure n-terminal domain conformational exchange]]
[[Category: Lortat-Jacob H]]
[[Category: Signaling protein]]
[[Category: Monneau YR]]

Latest revision as of 04:14, 21 November 2024

Murin CXCL13 solution structure featuring a folded N-terminal domain

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