5vei: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: '''Unreleased structure''' The entry 5vei is ON HOLD Authors: Liu, Y., Tempel, W., Huang, H., Gu, J., Liu, K., Sidhu, S.S., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Struct... |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2== | |||
<StructureSection load='5vei' size='340' side='right'caption='[[5vei]], [[Resolution|resolution]] 1.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5vei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4igz 4igz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VEI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vei OCA], [https://pdbe.org/5vei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vei RCSB], [https://www.ebi.ac.uk/pdbsum/5vei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vei ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref> <ref>PMID:12475393</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Tempel | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra C]] | |||
[[Category: Edwards AM]] | |||
[[Category: Gu J]] | |||
[[Category: Huang H]] | |||
[[Category: Liu K]] | |||
[[Category: Liu Y]] | |||
[[Category: Min J]] | |||
[[Category: Sidhu SS]] | |||
[[Category: Tempel W]] | |||
Latest revision as of 13:47, 4 October 2023
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
| ||||||||||||
