1ucu: Difference between revisions

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[[Image:1ucu.gif|left|200px]]


{{Structure
==R-type straight flagellar filament made of full-length flagellin==
|PDB= 1ucu |SIZE=350|CAPTION= <scene name='initialview01'>1ucu</scene>, resolution 4.0&Aring;
<SX load='1ucu' size='340' side='right' viewer='molstar' caption='[[1ucu]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1ucu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UCU FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ucu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ucu OCA], [https://pdbe.org/1ucu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ucu RCSB], [https://www.ebi.ac.uk/pdbsum/1ucu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ucu ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ucu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ucu OCA], [http://www.ebi.ac.uk/pdbsum/1ucu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ucu RCSB]</span>
[https://www.uniprot.org/uniprot/FLIC_SALTY FLIC_SALTY] Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uc/1ucu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ucu ConSurf].
<div style="clear:both"></div>


'''R-type straight flagellar filament made of full-length flagellin'''
==See Also==
 
*[[Flagellin 3D structures|Flagellin 3D structures]]
 
__TOC__
==Overview==
</SX>
The bacterial flagellar filament is a helical propeller for bacterial locomotion. It is a helical assembly of a single protein, flagellin, and its tubular structure is formed by 11 protofilaments in two distinct conformations, L- and R-type, for supercoiling. The X-ray crystal structure of a flagellin fragment lacking about 100 terminal residues revealed the protofilament structure, but the full filament structure is still essential for understanding the mechanism of supercoiling and polymerization. Here we report a complete atomic model of the R-type filament by electron cryomicroscopy. A density map obtained from image data up to 4 A resolution shows the feature of alpha-helical backbone and some large side chains. The atomic model built on the map reveals intricate molecular packing and an alpha-helical coiled coil formed by the terminal chains in the inner core of the filament, with its intersubunit hydrophobic interactions having an important role in stabilizing the filament.
[[Category: Large Structures]]
 
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
==About this Structure==
[[Category: Maki-Yonekura S]]
1UCU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UCU OCA].
[[Category: Namba K]]
 
[[Category: Yonekura K]]
==Reference==
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy., Yonekura K, Maki-Yonekura S, Namba K, Nature. 2003 Aug 7;424(6949):643-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12904785 12904785]
[[Category: Salmonella typhimurium]]
[[Category: Single protein]]
[[Category: Maki-Yonekura, S.]]
[[Category: Namba, K.]]
[[Category: Yonekura, K.]]
[[Category: cryo-electron microscopy]]
[[Category: flagellar filament]]
[[Category: flagellin]]
[[Category: helical reconstruction]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:08:46 2008''
Retrieved from "https://proteopedia.org/1ucu"