5wyg: Difference between revisions
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==The crystal structure of the apo form of Mtb MazF== | ==The crystal structure of the apo form of Mtb MazF== | ||
<StructureSection load='5wyg' size='340' side='right' caption='[[5wyg]], [[Resolution|resolution]] 2.36Å' scene=''> | <StructureSection load='5wyg' size='340' side='right'caption='[[5wyg]], [[Resolution|resolution]] 2.36Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5wyg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYG OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5wyg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WYG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WYG FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.356Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wyg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wyg OCA], [https://pdbe.org/5wyg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wyg RCSB], [https://www.ebi.ac.uk/pdbsum/5wyg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wyg ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MAZF7_MYCTU MAZF7_MYCTU] Toxic component of a type II toxin-antitoxin (TA) module. Upon expression in E.coli and M.smegmatis inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE7 (PubMed:19016878, PubMed:20011113). Probably an endoribonuclease (By similarity).[UniProtKB:P9WIH9]<ref>PMID:19016878</ref> <ref>PMID:20011113</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: | [[Category: Chen R]] | ||
[[Category: | [[Category: Tu J]] | ||
[[Category: | [[Category: Xie W]] | ||
Latest revision as of 07:51, 22 November 2023
The crystal structure of the apo form of Mtb MazF
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