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==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG and beta-1,4-mannobiose==
==The structure of GH113 beta-mannanase AaManA from Alicyclobacillus acidocaldarius in complex with ManIFG and beta-1,4-mannobiose==
<StructureSection load='4cd7' size='340' side='right' caption='[[4cd7]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4cd7' size='340' side='right'caption='[[4cd7]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cd7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CD7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4cd7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alicyclobacillus_acidocaldarius Alicyclobacillus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CD7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cd4|4cd4]], [[4cd5|4cd5]], [[4cd6|4cd6]], [[4cd8|4cd8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=IFM:5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE'>IFM</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd7 OCA], [https://pdbe.org/4cd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cd7 RCSB], [https://www.ebi.ac.uk/pdbsum/4cd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd7 OCA], [http://pdbe.org/4cd7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cd7 RCSB], [http://www.ebi.ac.uk/pdbsum/4cd7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5H1I6_9BACL A5H1I6_9BACL]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 27009]]
[[Category: Alicyclobacillus acidocaldarius]]
[[Category: Mannan endo-1,4-beta-mannosidase]]
[[Category: Large Structures]]
[[Category: Davies, G J]]
[[Category: Davies GJ]]
[[Category: Gilbert, H J]]
[[Category: Gilbert HJ]]
[[Category: Iglesias-Fernandez, J]]
[[Category: Iglesias-Fernandez J]]
[[Category: Jackson, A]]
[[Category: Jackson A]]
[[Category: Lowe, E C]]
[[Category: Lowe EC]]
[[Category: Rovira, C]]
[[Category: Rovira C]]
[[Category: Stepper, J]]
[[Category: Stepper J]]
[[Category: Thompson, A J]]
[[Category: Thompson AJ]]
[[Category: White, J M]]
[[Category: White JM]]
[[Category: Williams, R J]]
[[Category: Williams RJ]]
[[Category: Williams, S J]]
[[Category: Williams SJ]]
[[Category: Beta-mannosidase]]
[[Category: Biocatalysis]]
[[Category: Cazy]]
[[Category: Conformation]]
[[Category: Enzyme-carbohydrate interaction]]
[[Category: Gh113]]
[[Category: Gh26]]
[[Category: Glycosidase inhibition]]
[[Category: Glycoside hydrolase]]
[[Category: Hydrolase]]
[[Category: Mannosidase]]
[[Category: Quantum mechanic]]
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