Sandbox1996: Difference between revisions

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<scene name='75/756546/Inprogess1/1'></scene>Diuril (Chlorothiazide)<scene name='75/756546/Drug/1'></scene>

== Structure ==

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===Diabetes Insipidus===

Diabetes Insipidus is a rare disorder caused by the kidney’s inability to retain water. There are four different types of diabetes Insipidus; Central, Nephrogenic, Dipsogenic and Gestational. High concentrations of sodium and potassium are characteristic of all types of Diabetes Insipidus. Treatment with Diuril demonstrates a decrease in saluresis, i.e the excretion of sodium and chloride, within approximately eight hours following its initial dose, and a decrease in kaliuresis, the excretion of potassium ions, approximately fifteen hours following its initial dose.<ref name = "ten"> Crawford, J.D., Kennedy, G.C., and Hill, L.E. (1960) Clinical results of treatment of diabetes insipidus with drugs of the chlorothiazide series, N. Engl. J. Med. 262, 737-743. </ref>.

Diabetes Insipidus is a rare disorder caused by the kidney’s inability to retain water. There are four different types of diabetes Insipidus; Central, Nephrogenic, Dipsogenic and Gestational. High concentrations of sodium and potassium in the blood are characteristic of all types of Diabetes Insipidus. Treatment with Diuril demonstrates a decrease in saluresis, i.e the excretion of sodium and chloride, within approximately eight hours following its initial dose, and a decrease in kaliuresis, the excretion of potassium ions, approximately fifteen hours following its initial dose.<ref name = "ten"> Crawford, J.D., Kennedy, G.C., and Hill, L.E. (1960) Clinical results of treatment of diabetes insipidus with drugs of the chlorothiazide series, N. Engl. J. Med. 262, 737-743. </ref>.

===Kidney Stones===

Sandbox1996: Difference between revisions

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@@ Line 1: / Line 1: @@
 <scene name='75/756546/Inprogess1/1'></scene>Diuril (Chlorothiazide)<scene name='75/756546/Drug/1'></scene>
-<StructureSection load='1stp' size='340' side='right' caption='The structure of chlorothizade bound to glutamate receptor 2 (PDB code 3Ik6)' scene=''>
+<StructureSection load='1stp' size='340' side='right' caption='The structure of chlorothiazide bound to glutamate receptor 2 (PDB code 3Ik6)' scene=''>
 == Structure ==
@@ Line 29: / Line 29: @@
 ===Diabetes Insipidus===
-Diabetes Insipidus is a rare disorder caused by the kidney’s inability to retain water. There are four different types of diabetes Insipidus; Central, Nephrogenic, Dipsogenic and Gestational. High concentrations of sodium and potassium are characteristic of all types of Diabetes Insipidus. Treatment with Diuril demonstrates a decrease in saluresis, i.e the excretion of sodium and chloride, within approximately eight hours following its initial dose, and a decrease in kaliuresis, the excretion of potassium ions, approximately fifteen hours following its initial dose.<ref name = "ten"> Crawford, J.D., Kennedy, G.C., and Hill, L.E. (1960) Clinical results of treatment of diabetes insipidus with drugs of the chlorothiazide series, N. Engl. J. Med. 262, 737-743. </ref>.
+Diabetes Insipidus is a rare disorder caused by the kidney’s inability to retain water. There are four different types of diabetes Insipidus; Central, Nephrogenic, Dipsogenic and Gestational. High concentrations of sodium and potassium in the blood are characteristic of all types of Diabetes Insipidus. Treatment with Diuril demonstrates a decrease in saluresis, i.e the excretion of sodium and chloride, within approximately eight hours following its initial dose, and a decrease in kaliuresis, the excretion of potassium ions, approximately fifteen hours following its initial dose.<ref name = "ten"> Crawford, J.D., Kennedy, G.C., and Hill, L.E. (1960) Clinical results of treatment of diabetes insipidus with drugs of the chlorothiazide series, N. Engl. J. Med. 262, 737-743. </ref>.
 ===Kidney Stones===