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'''Unreleased structure'''


The entry 5vke is ON HOLD
==Open conformation of KcsA deep-inactivated==
<StructureSection load='5vke' size='340' side='right'caption='[[5vke]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5vke]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VKE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VKE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1EM:(1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL+MYRISTATE'>1EM</scene>, <scene name='pdbligand=F09:NONAN-1-OL'>F09</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vke FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vke OCA], [https://pdbe.org/5vke PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vke RCSB], [https://www.ebi.ac.uk/pdbsum/5vke PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vke ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref>


Authors: Cuello, L.G., Perozo, E., Cortes, D.M.
==See Also==
 
*[[Antibody 3D structures|Antibody 3D structures]]
Description: Open conformation of KcsA deep-inactivated
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
[[Category: Unreleased Structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
[[Category: Cuello, L.G]]
== References ==
[[Category: Perozo, E]]
<references/>
[[Category: Cortes, D.M]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Streptomyces lividans]]
[[Category: Cortes DM]]
[[Category: Cuello LG]]
[[Category: Perozo E]]
Retrieved from "https://proteopedia.org/5vke"