5vmb: Difference between revisions
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New page: '''Unreleased structure''' The entry 5vmb is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease Description: Crystal structure of a glycine hydroxymethyltransfe... |
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==Crystal structure of a glycine hydroxymethyltransferase from Acinetobacter baumannii== | |||
<StructureSection load='5vmb' size='340' side='right'caption='[[5vmb]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5vmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VMB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vmb OCA], [https://pdbe.org/5vmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vmb RCSB], [https://www.ebi.ac.uk/pdbsum/5vmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vmb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/V5VBJ2_ACIBA V5VBJ2_ACIBA] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.[HAMAP-Rule:MF_00051] | |||
==See Also== | |||
*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Acinetobacter baumannii]] | ||
[[Category: Large Structures]] | |||
Latest revision as of 13:51, 4 October 2023
Crystal structure of a glycine hydroxymethyltransferase from Acinetobacter baumannii
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