5voz: Difference between revisions
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New page: '''Unreleased structure''' The entry 5voz is ON HOLD Authors: Jianhua Zhao Description: Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 3) [[Categ... |
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==Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 3)== | |||
<SX load='5voz' size='340' side='right' viewer='molstar' caption='[[5voz]], [[Resolution|resolution]] 7.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5voz]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VOZ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5voz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5voz OCA], [https://pdbe.org/5voz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5voz RCSB], [https://www.ebi.ac.uk/pdbsum/5voz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5voz ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VATA_YEAST VATA_YEAST] Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase (vacuolar ATPase) is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mV, inside positive and acidic, in the vacuolar membrane vesicles. It may participate in maintenance of cytoplasmic Ca(2+) homeostasis. This is a catalytic subunit.<ref>PMID:1534148</ref> PI-SceI is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates "homing", a genetic event that converts a VMA1 allele lacking VDE into one that contains it.<ref>PMID:1534148</ref> | |||
==See Also== | |||
*[[ATPase 3D structures|ATPase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</SX> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Zhao J]] | |||
