1v89: Difference between revisions

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[[Image:1v89.gif|left|200px]]


{{Structure
==Solution Structure of the Pleckstrin Homology Domain of Human KIAA0053 Protein==
|PDB= 1v89 |SIZE=350|CAPTION= <scene name='initialview01'>1v89</scene>
<StructureSection load='1v89' size='340' side='right'caption='[[1v89]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1v89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V89 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= KAZUSA cDNA ha01417 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v89 OCA], [https://pdbe.org/1v89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v89 RCSB], [https://www.ebi.ac.uk/pdbsum/1v89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v89 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v89 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v89 OCA], [http://www.ebi.ac.uk/pdbsum/1v89 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v89 RCSB]</span>
[https://www.uniprot.org/uniprot/RHG25_HUMAN RHG25_HUMAN] GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity).
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Solution Structure of the Pleckstrin Homology Domain of Human KIAA0053 Protein'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/1v89_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1V89 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V89 OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v89 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hirota, H.]]
[[Category: Hirota H]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Li, H.]]
[[Category: Li H]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: phosphatidylinositol binding]]
[[Category: pleckstrin homology domain]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:20:50 2008''
Retrieved from "https://proteopedia.org/1v89"