5nzy: Difference between revisions

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New page: '''Unreleased structure''' The entry 5nzy is ON HOLD Authors: Newman, J.A., Aitkenhead, H., Kupinska, K., Burgess-Brown, N.A., Talon, R., Krojer, T., von Delft, F., Arrowsmith, C.H., Ed...
 
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'''Unreleased structure'''


The entry 5nzy is ON HOLD
==Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime==
 
<StructureSection load='5nzy' size='340' side='right'caption='[[5nzy]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
Authors: Newman, J.A., Aitkenhead, H., Kupinska, K., Burgess-Brown, N.A., Talon, R., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5nzy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZY FirstGlance]. <br>
Description: Crystal structure of DNA cross-link repair protein 1A in complex with Cefotaxime
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.551&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
[[Category: Arrowsmith, C.H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzy OCA], [https://pdbe.org/5nzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nzy RCSB], [https://www.ebi.ac.uk/pdbsum/5nzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzy ProSAT]</span></td></tr>
[[Category: Burgess-Brown, N.A]]
</table>
[[Category: Von Delft, F]]
== Function ==
[[Category: Aitkenhead, H]]
[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
[[Category: Talon, R]]
== References ==
[[Category: Gileadi, O]]
<references/>
[[Category: Newman, J.A]]
__TOC__
[[Category: Edwards, A]]
</StructureSection>
[[Category: Krojer, T]]
[[Category: Homo sapiens]]
[[Category: Bountra, C]]
[[Category: Large Structures]]
[[Category: Kupinska, K]]
[[Category: Aitkenhead H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Burgess-Brown NA]]
[[Category: Edwards A]]
[[Category: Gileadi O]]
[[Category: Krojer T]]
[[Category: Kupinska K]]
[[Category: Newman JA]]
[[Category: Talon R]]
[[Category: Von Delft F]]
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