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[[Image:1vl4.gif|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF A PUTATIVE MODULATOR OF A DNA GYRASE (TM0727) FROM THERMOTOGA MARITIMA MSB8 AT 1.95 A RESOLUTION==
|PDB= 1vl4 |SIZE=350|CAPTION= <scene name='initialview01'>1vl4</scene>, resolution 1.95&Aring;
<StructureSection load='1vl4' size='340' side='right'caption='[[1vl4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1vl4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VL4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VL4 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
|GENE= TM0727 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vl4 OCA], [https://pdbe.org/1vl4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vl4 RCSB], [https://www.ebi.ac.uk/pdbsum/1vl4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vl4 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vl4 TOPSAN]</span></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0312 TldD]</span>
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vl4 OCA], [http://www.ebi.ac.uk/pdbsum/1vl4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vl4 RCSB]</span>
[https://www.uniprot.org/uniprot/Q9WZI6_THEMA Q9WZI6_THEMA]  
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal structure of PMBA-related protein (TM0727) from Thermotoga maritima at 1.95 A resolution'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vl/1vl4_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1VL4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VL4 OCA].
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==Reference==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vl4 ConSurf].
Crystal structure of a putative modulator of DNA gyrase (pmbA) from Thermotoga maritima at 1.95 A resolution reveals a new fold., Rife C, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Jaroszewski L, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, Miller MD, Moy K, Nigoghossian E, Paulsen J, Quijano K, Reyes R, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA, Proteins. 2005 Nov 1;61(2):444-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16104019 16104019]
<div style="clear:both"></div>
[[Category: Single protein]]
__TOC__
[[Category: Thermotoga maritima msb8]]
</StructureSection>
[[Category: JCSG, Joint Center for Structural Genomics.]]
[[Category: Large Structures]]
[[Category: jcsg]]
[[Category: Thermotoga maritima MSB8]]
[[Category: joint center for structural genomic]]
[[Category: pmba-related protein]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
[[Category: tm0727]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:25:56 2008''

Latest revision as of 09:15, 22 May 2024

CRYSTAL STRUCTURE OF A PUTATIVE MODULATOR OF A DNA GYRASE (TM0727) FROM THERMOTOGA MARITIMA MSB8 AT 1.95 A RESOLUTION

1vl4, resolution 1.95Å

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