Variable lymphocyte receptor: Difference between revisions

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<StructureSection load='g3a' size='350' side='right' scene='Variable_Lymphocyte_Receptors/3g3a_biological_unit/3' caption='Variable lymphocyte receptor of lamprey (grey) bound to a protein antigen (green) ([[3g3a]]), resolution 2.20&Aring;'>
<StructureSection load='' size='350' side='right' scene='45/456531/Cv/1' caption='Variable lymphocyte receptor of lamprey (grey) bound to a protein antigen (green) ([[3g3a]]), resolution 2.20&Aring;'>
'''Variable lymphocyte receptors''' (VLRs) are [[leucine-rich repeat]] (LRR) family proteins that mediate adaptive immune responses in the jawless vertebrates, lampreys and hagfish. <ref>PMID: 17192264</ref>
'''Variable lymphocyte receptors''' (VLRs) are [[leucine-rich repeat]] (LRR) family proteins that mediate adaptive immune responses in the jawless vertebrates, lampreys and hagfish. <ref>PMID: 17192264</ref>


[[Image:3g3a biol unitsurf.png|370px|right|thumb| [[Lamprey Variable Lymphocyte Receptor]] in complex with a protein antigen ([[3g3a]])]]
<scene name='45/456531/Cv/3'>Leucines highlighted in magenta</scene>.
 
[[Image:3g3a biol unitsurf.png|370px|left|thumb| [[Lamprey Variable Lymphocyte Receptor]] in complex with a protein antigen ([[3g3a]])]]
{{Clear}}
{{Clear}}


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*[[Antibody]]
*[[Antibody]]
*[[Forkhead box protein]]
*[[Forkhead box protein]]
 
==3D structures of variable lymphocyte receptor==
[[Variable lymphocyte receptor 3D structures]]
</StructureSection>
</StructureSection>


==3D structures of variable lymphocyte receptor==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Variable lymphocyte receptor
**[[3m19]], [[3g39]], [[2r9u]], [[3wo9]], [[4k5u]], [[4k79]] - mlVLR ectodomain – marine lamprey<br />
**[[3m18]], [[3g3a]] – mlVLR ectodomain + lysozyme<br />
**[[3g3b]] - mlVLR ectodomain (mutant) + lysozyme<br />
**[[3e6j]] - mlVLR ectodomain + trisaccharide<br />
**[[2o6q]], [[2o6r]], [[2o6s]] – IhVLR leucine-rich repeat – inshore hagfish<br />
**[[3twi]] – VLR B antigen-binding domain + BCLA protein – ''Bacillus anthracis''<br />
*Variable lymphocyte receptor chimera
**[[2z62]], [[2z63]], [[2z66]] – IhVLR/hTLR4<br />
**[[4qxe]] – IhVLR/G-protein coupled receptor<br />
**[[4qxf]] – IhVLR/G-protein coupled receptor + r-spondin<br />
**[[3ul7]], [[3ul8]], [[3ul9]] – IhVLR/hTLR4 (mutant)<br />
**[[3ula]] – IhVLR/hTLR4 (mutant) + eritoran<br />
**[[2z80]], [[2z81]], [[2z82]], [[3a78]], [[3a7c]] – IhVLR/hTLR2<br />
**[[2z65]], [[5ijb]], [[5ijc]], [[5ijd]] – IhVLR/hTLR4 + lymphocyte antigen 96<br />
**[[2z7x]] – IhVLR/hTLR1 + IhVLR/hTLR2 + tri-acylated lipopeptide<br />
**[[3a79]] - IhVLR/hTLR2 + IhVLR/hTLR6 + tri-acylated lipopeptide<br />
**[[3v44]], [[3v47]] - VLR/TLR5B – zebra fish<br />
**[[4arn]], [[4arr]] - DmVLRB/TLR – ''Drosophila melanogaster''<br />
**[[4bv4]] - DmVLRB/TLR + spaetzle<br />
**[[4j4l]] - VLRB/internalin + interleukin-6 – ''Listeria monocytogenes''<br />
}}
Articles in Proteopedia concerning Variable lymphocyte receptors include:
Articles in Proteopedia concerning Variable lymphocyte receptors include:
*[[Lamprey Variable Lymphocyte Receptor]]
*[[Lamprey Variable Lymphocyte Receptor]]