5v2i: Difference between revisions

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==Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria==
==Crystal structure of a mutant glycosylasparaginase (G172D) that causes the genetic disease Aspartylglucosaminuria==
<StructureSection load='5v2i' size='340' side='right' caption='[[5v2i]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
<StructureSection load='5v2i' size='340' side='right'caption='[[5v2i]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5v2i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V2I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V2I FirstGlance]. <br>
<table><tr><td colspan='2'>[[5v2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica Elizabethkingia meningoseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V2I FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v2i OCA], [http://pdbe.org/5v2i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v2i RCSB], [http://www.ebi.ac.uk/pdbsum/5v2i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v2i ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v2i OCA], [https://pdbe.org/5v2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v2i RCSB], [https://www.ebi.ac.uk/pdbsum/5v2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v2i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Asparaginase 3D structures|Asparaginase 3D structures]]
*[[Glycosylasparaginase|Glycosylasparaginase]]
*[[Glycosylasparaginase|Glycosylasparaginase]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Guo, H]]
[[Category: Elizabethkingia meningoseptica]]
[[Category: Pande, S]]
[[Category: Large Structures]]
[[Category: Beta-aha]]
[[Category: Guo H]]
[[Category: Catalytic mechanism]]
[[Category: Pande S]]
[[Category: Hydrolase]]
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