1wi9: Difference between revisions

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[[Image:1wi9.jpg|left|200px]]


{{Structure
==Solution structure of the PCI domain from mouse hypothetical protein AAH51541==
|PDB= 1wi9 |SIZE=350|CAPTION= <scene name='initialview01'>1wi9</scene>
<StructureSection load='1wi9' size='340' side='right'caption='[[1wi9]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1wi9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WI9 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= RIKEN cDNA 1110001I20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi9 OCA], [https://pdbe.org/1wi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wi9 RCSB], [https://www.ebi.ac.uk/pdbsum/1wi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wi9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wi9 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi9 OCA], [http://www.ebi.ac.uk/pdbsum/1wi9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1wi9 RCSB]</span>
[https://www.uniprot.org/uniprot/DDRGK_MOUSE DDRGK_MOUSE] Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIB, the inhibitor of NF-kappa-B (By similarity). May also play a role in the cellular response to endoplasmic reticulum stress (PubMed:21494687).[UniProtKB:Q96HY6]<ref>PMID:21494687</ref>
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Solution structure of the PCI domain from mouse hypothetical protein AAH51541'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wi9_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1WI9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI9 OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wi9 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Muto Y]]
[[Category: Muto, Y.]]
[[Category: Shirouzu M]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Suzuki S]]
[[Category: Shirouzu, M.]]
[[Category: Terada T]]
[[Category: Suzuki, S.]]
[[Category: Yokoyama S]]
[[Category: Terada, T.]]
[[Category: Yokoyama, S.]]
[[Category: helix-turn-helix motif]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:36:36 2008''
Retrieved from "https://proteopedia.org/1wi9"