Protein G: Difference between revisions

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<StructureSection load='1uwx' size='340' side='right' caption='Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code [[1uwx]]).' scene=''>
<StructureSection load='1uwx' size='340' side='right' caption='Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code [[1uwx]]).' scene=''>
'''Protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.  
'''Protein G''' or '''immunoglobulin-binding protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.  


For ProG  immunoglobulin-binding domain see [[Chameleon peptide]].
For ProG  immunoglobulin-binding domain see [[Chameleon peptide]].
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Protein G
*Streptococcus Protein G domain I or GBI residues 2-68
 
**[[3gb1]] – StProG domain B1 – Streptococcus - NMR<br />
**[[8ug0]], [[8ug2]] – StProG domain B1 (mutant)<br />
**[[6hka]] – StProG domain B1/ATM peptide<br />
**[[6hpj]] – StProG domain B1/ASF-1 + RNA - NMR<br />
**[[6u8c]] – StProG + antibody<br />
 
*Streptococcus Protein G residues 56-118
 
**[[1uwx]] – StProG + Igg1 Fab<br />
**[[1qkz]] – StProG (mutant) + Igg1 Fab + peptide antigen<br />
 
*Streptococcus Protein G residues 189-244
 
**[[1em7]] – StProG (mutant) <br />
 
*Streptococcus Protein G residues 228-282
 
**[[1mpe]], [[1pga]], [[1pgb]], [[1q10]], [[2ju6]], [[2rmm]], [[2rpv]], [[2j52]], [[2j53]], [[2k0p]] - StProG  <br />
**[[1mvk]] – StProG (mutant) <br />
**[[7qtr]], [[7qts]] - StProG - NMR<br />
**[[1mvk]] – StProG (mutant) - NMR<br />
**[[5jxv]] – StProG/ubiquitin-like protein - NMR<br />
**[[2den]] – StProG/ubiquitin-like protein + ubiquitin - NMR<br />
**[[9cht]] – StProG/p53 + E3A + protein E6 – Cryo EM<br />
 
*Streptococcus Protein G residues 254-299


**[[1pgx]] – StProG – ''Streptococcus''<br />
**[[1gb1]], [[2gb1]], [[2igg]], [[2igh]] - SgProG immunoglobulin-binding domain – ''Streptomyces griseus'' – NMR<br />
**[[2igg]], [[2igh]] - SgProG immunoglobulin-binding domains II+III – NMR<br />
**[[1pga]], [[1pgb]], [[2on8]], [[3fil]] - StProG immunoglobulin-binding domain <br />
**[[1zxh]], [[2ju6]], [[2rmm]], [[2jsv]], [[2rpv]], [[2kq4]], [[2kwd]] - StProG immunoglobulin-binding domain (mutant) - NMR<br />
**[[2klk]] - StProG immunoglobulin-binding domain - NMR<br />
**[[2onq]] - StProG immunoglobulin-binding domain (mutant) <br />
**[[2plp]] - StProG immunoglobulin-binding domain I - NMR<br />
**[[2igd]] - StProG immunoglobulin-binding domain III<br />
**[[1p7e]], [[1p7f]], [[2lum]] - StProG immunoglobulin-binding domain III - NMR<br />
**[[1gjs]], [[1gjt]] - StProG albumin-binding domain - NMR<br />
**[[1gjs]], [[1gjt]] - StProG albumin-binding domain - NMR<br />
**[[1igd]] - StProG immunoglobulin-binding domain III<br />
**[[3mp3]] - StProG domain B1 <br />
**[[3gb1]] – StProG domain B1 – NMR<br />
**[[1gb4]], [[1fcl]], [[1fd6]], [[1mpe]], [[1q10]], [[2j52]], [[2j53]], [[2k0p]] – StProG domain B1 (mutant) – NMR<br />
**[[1em7]], [[1mvk]], [[3v3x]] – StProG domain B1 (mutant) <br />
**[[2gi9]], [[2qmt]] – ProG domain B1 (mutant) – ''Staphylococcus aureus''<br />


*Protein G complex with immunoglobulin
*Streptococcus Protein G residues 300-357


**[[1fcc]] – StProG C2 fragment + Igg1 Fc<br />
**[[1igd]], [[1pgx]], [[2igd]], [[3fil]] - StProG <br />
**[[1uwx]] – StProG domain II + Igg1 Fab<br />
**[[3v3x]], [[6c9o]], [[6nl6]], [[6nl7]], [[6nl8]], [[6nl9]], [[6nlb]], [[7da8]], [[9i2i]], [[9t8z]], [[12lo]] – StProG (mutant) <br />
**[[2plp]], [[8um7]], [[8um9]], [[8uma]], [[8umb]], [[8ums]] - StProG - NMR<br />
**[[1fcl]], [[1fd6]], [[2jsv]], [[2kq4]], [[2kwd]] - StProG (mutant) - NMR<br />
**[[1igc]] – StProG domain III + Igg1 Fab<br />
**[[1igc]] – StProG domain III + Igg1 Fab<br />
**[[9rxk]] – StProG + Pit2<br />
**[[3ui3]] – StProG/VAPD <br />
**[[2kn4]] – StProG domain B1/splicing factor - NMR<br />
**[[9g4t]] – StProG/CSOSCA – Cryo EM <br />
**[[6v9i]] – StProG/cullin-5 + RBX2 – Cryo EM <br />
**[[2khu]], [[2mbb]] – StProG/DNA polymerase iota <br />
**[[2khw]] – StProG/DNA polymerase iota + ubiquitin<br />
**[[5lde]] – StProG/VFLIP <br />
*Streptococcus Protein G residues 328-384
**[[9kl7]], [[9kls]], [[9klt]], [[9klu]] - StProG (mutant)<br />
*Streptococcus Protein G residues 367-430
**[[2on8]] - StProG  <br />
**[[2onq]] – StProG (mutant) <br />
**[[1gb4]], [[6njf]] – StProG (mutant) – NMR<br />
**[[1fcc]] – StProG + Igg1 Fc<br />
*Streptococcus Protein G domain III or GB3 residues 443-497
**[[8wcj]] - StProG (mutant)<br />
**[[1p7e]], [[1p7f]], [[2lum]] - StProG - NMR<br />
**[[1zxh]] - StProG (mutant) - NMR<br />
**[[8tfr]] - StProG + antibody<br />
**[[6uyg]] - StProG + envelope glycoprotein + antibody<br />
**[[6w00]] - StProG + peptide + antibody<br />
*Protein G
**[[1gb1]], [[2gb1]], [[2igg]], [[2igh]] - SgProG immunoglobulin-binding domain – Streptomyces griseus – NMR<br />
**[[2igg]], [[2igh]] - SgProG immunoglobulin-binding domains II+III – NMR<br />
**[[2gi9]], [[2qmt]] – SaProG domain B1 (mutant) – Staphylococcus aureus<br />
**[[2klk]] - SaProG immunoglobulin-binding domain - NMR<br />
**[[9fa8]] - EcProG antibody-binding domain C2 1-65 – Escherichia coli - NMR<br />
**[[9a9t]], [[9a9u]] - EcProG antibody-binding domain C2 1-65 (mutant) – NMR<br />
**[[8r40]] - ProG immunoglobulin-binding domain III 201-281+ diabody – Rabies virus<br />
}}
}}
[[Category:Topic Page]]
== References ==
== References ==
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[[Category:Topic Page]]
[[Category:Topic Page]]
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