5och: Difference between revisions
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New page: '''Unreleased structure''' The entry 5och is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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The | ==The crystal structure of human ABCB8 in an outward-facing state== | ||
<StructureSection load='5och' size='340' side='right'caption='[[5och]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5och]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OCH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5och FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5och OCA], [https://pdbe.org/5och PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5och RCSB], [https://www.ebi.ac.uk/pdbsum/5och PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5och ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MITOS_HUMAN MITOS_HUMAN] ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). Plays a role in mitochondrial iron transport (PubMed:30623799). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).[UniProtKB:Q9CXJ4]<ref>PMID:30623799</ref> <ref>PMID:31435016</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith CH]] | |||
[[Category: Barr A]] | |||
[[Category: Borkowska O]] | |||
[[Category: Bountra C]] | |||
[[Category: Burgess-Brown NA]] | |||
[[Category: Carpenter EP]] | |||
[[Category: Chalk R]] | |||
[[Category: Chu A]] | |||
[[Category: Edwards AM]] | |||
[[Category: Faust B]] | |||
[[Category: Mukhopadhyay S]] | |||
[[Category: Pike ACW]] | |||
[[Category: Quiqley AM]] | |||
[[Category: Shintre CA]] | |||
[[Category: Shrestha L]] | |||
Latest revision as of 09:39, 6 December 2023
The crystal structure of human ABCB8 in an outward-facing state
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