1x9j: Difference between revisions

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[[Image:1x9j.gif|left|200px]]


{{Structure
==Structure of butyrate kinase 2 reveals both open- and citrate-induced closed conformations: implications for substrate-induced fit conformational changes==
|PDB= 1x9j |SIZE=350|CAPTION= <scene name='initialview01'>1x9j</scene>, resolution 3.00&Aring;
<StructureSection load='1x9j' size='340' side='right'caption='[[1x9j]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
<table><tr><td colspan='2'>[[1x9j]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X9J FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Butyrate_kinase Butyrate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.7 2.7.2.7] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
|GENE= buk2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x9j OCA], [https://pdbe.org/1x9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x9j RCSB], [https://www.ebi.ac.uk/pdbsum/1x9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x9j ProSAT]</span></td></tr>
|RELATEDENTRY=[[1saz|1SAZ]], [[1g99|1G99]]
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x9j OCA], [http://www.ebi.ac.uk/pdbsum/1x9j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1x9j RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/BUK2_THEMA BUK2_THEMA]
 
== Evolutionary Conservation ==
'''Structure of butyrate kinase 2 reveals both open- and citrate-induced closed conformations: implications for substrate-induced fit conformational changes'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x9/1x9j_consurf.spt"</scriptWhenChecked>
1X9J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X9J OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Butyrate kinase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x9j ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
[[Category: Diao, J S.]]
[[Category: Diao JS]]
[[Category: Hasson, M S.]]
[[Category: Hasson MS]]
[[Category: Sanders, D A.]]
[[Category: Sanders DA]]
[[Category: acetate kinase]]
[[Category: actin) superfamily]]
[[Category: askha (acetate and sugar kinase]]
[[Category: butyrate]]
[[Category: butyrate kinase]]
[[Category: enzyme mechanism]]
[[Category: hsc70]]
[[Category: isobutyrate]]
[[Category: isobutyrate kinase]]
[[Category: two similar domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:46:35 2008''
Retrieved from "https://proteopedia.org/1x9j"