5w3g: Difference between revisions
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==Solution Structure of ETS Transcription Factor PU.1== | |||
<StructureSection load='5w3g' size='340' side='right'caption='[[5w3g]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5w3g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W3G FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w3g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3g OCA], [https://pdbe.org/5w3g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w3g RCSB], [https://www.ebi.ac.uk/pdbsum/5w3g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3g ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Lau | == Disease == | ||
[[Category: | [https://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE] Note=Involved in murine acute Friend erythroleukemia. It is a target region for SFFV proviral insertion. | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/SPI1_MOUSE SPI1_MOUSE] Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.<ref>PMID:8626664</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Lau DKW]] | |||
[[Category: McIntosh LP]] | |||
[[Category: Okon M]] | |||
Latest revision as of 10:28, 14 June 2023
Solution Structure of ETS Transcription Factor PU.1
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