5wnk: Difference between revisions
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New page: '''Unreleased structure''' The entry 5wnk is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115== | |||
<StructureSection load='5wnk' size='340' side='right'caption='[[5wnk]], [[Resolution|resolution]] 3.11Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5wnk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WNK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B6J:3,3-(2,4-diaminopteridine-6,7-diyl)diphenol'>B6J</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wnk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wnk OCA], [https://pdbe.org/5wnk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wnk RCSB], [https://www.ebi.ac.uk/pdbsum/5wnk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wnk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RIPK4_MOUSE RIPK4_MOUSE] Involved in stratified epithelial development (By similarity). It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.<ref>PMID:12446564</ref> <ref>PMID:22197488</ref> | |||
==See Also== | |||
*[[Ankyrin repeat domain-containing protein 3D structures|Ankyrin repeat domain-containing protein 3D structures]] | |||
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Huang CS]] | |||
[[Category: Hymowitz SG]] | |||
Latest revision as of 14:16, 13 March 2024
Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115
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