5yc1: Difference between revisions
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New page: '''Unreleased structure''' The entry 5yc1 is ON HOLD Authors: Park, H.H., Kim, C.M. Description: TRAF4_GPIb complex Category: Unreleased Structures Category: Park, H.H [[Catego... |
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==TRAF4_GPIb complex== | |||
<StructureSection load='5yc1' size='340' side='right'caption='[[5yc1]], [[Resolution|resolution]] 2.51Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5yc1]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YC1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.506Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yc1 OCA], [https://pdbe.org/5yc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yc1 RCSB], [https://www.ebi.ac.uk/pdbsum/5yc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yc1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRAF4_HUMAN TRAF4_HUMAN] Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.<ref>PMID:12023963</ref> <ref>PMID:12801526</ref> <ref>PMID:16052631</ref> <ref>PMID:16157600</ref> <ref>PMID:18953416</ref> <ref>PMID:19937093</ref> | |||
==See Also== | |||
*[[TNF receptor-associated factor 3D structures|TNF receptor-associated factor 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Kim CM]] | |||
[[Category: Park HH]] | |||
