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==E. fae Cas1-Cas2/prespacer/target ternary complex revealing DNA sampling and half-integration states==
==E. fae Cas1-Cas2/prespacer/target ternary complex revealing DNA sampling and half-integration states==
<StructureSection load='5xvo' size='340' side='right' caption='[[5xvo]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='5xvo' size='340' side='right'caption='[[5xvo]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xvo]] is a 18 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XVO FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xvo]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_TX0027 Enterococcus faecalis TX0027]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XVO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xvn|5xvn]], [[5xvp|5xvp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvo OCA], [http://pdbe.org/5xvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xvo RCSB], [http://www.ebi.ac.uk/pdbsum/5xvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xvo OCA], [https://pdbe.org/5xvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xvo RCSB], [https://www.ebi.ac.uk/pdbsum/5xvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xvo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/E6GPD7_ENTFL E6GPD7_ENTFL]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01470] [[http://www.uniprot.org/uniprot/E6GPD6_ENTFL E6GPD6_ENTFL]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5xvo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5xvo" style="background-color:#fffaf0;"></div>
==See Also==
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ke, A]]
[[Category: Enterococcus faecalis TX0027]]
[[Category: Nam, K H]]
[[Category: Large Structures]]
[[Category: Ng, S]]
[[Category: Ke A]]
[[Category: Xiao, Y]]
[[Category: Nam KH]]
[[Category: Ca]]
[[Category: Ng S]]
[[Category: Crispr]]
[[Category: Xiao Y]]
[[Category: Immune system]]
Retrieved from "https://proteopedia.org/5xvo"