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[[Image:1ypf.gif|left|200px]]


{{Structure
==Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution==
|PDB= 1ypf |SIZE=350|CAPTION= <scene name='initialview01'>1ypf</scene>, resolution 1.80&Aring;
<StructureSection load='1ypf' size='340' side='right'caption='[[1ypf]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1ypf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YPF FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/GMP_reductase GMP reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.7 1.7.1.7] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
|GENE= guaC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ypf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypf OCA], [https://pdbe.org/1ypf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ypf RCSB], [https://www.ebi.ac.uk/pdbsum/1ypf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypf ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypf OCA], [http://www.ebi.ac.uk/pdbsum/1ypf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ypf RCSB]</span>
[https://www.uniprot.org/uniprot/GUAC_BACAN GUAC_BACAN] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity).
}}
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
'''Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution'''
Check<jmol>
 
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1ypf_consurf.spt"</scriptWhenChecked>
==About this Structure==
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
1YPF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPF OCA].  
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ypf ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: GMP reductase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Blagova EV]]
[[Category: Blagova, E V.]]
[[Category: Brannigan JA]]
[[Category: Brannigan, J A.]]
[[Category: Fogg MJ]]
[[Category: Fogg, M J.]]
[[Category: Grenha R]]
[[Category: Grenha, R.]]
[[Category: Levdikov VM]]
[[Category: Levdikov, V M.]]
[[Category: Wilkinson AJ]]
[[Category: SPINE, Structural Proteomics in Europe.]]
[[Category: Wilson KS]]
[[Category: Wilkinson, A J.]]
[[Category: Wilson, K S.]]
[[Category: guac]]
[[Category: nucleoside]]
[[Category: nucleotide and nucleoside interconversion]]
[[Category: nucleotide]]
[[Category: purine]]
[[Category: pyrimidine]]
[[Category: spine]]
[[Category: structural genomic]]
[[Category: structural proteomics in europe]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:16:49 2008''

Latest revision as of 08:12, 25 October 2023

Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution

1ypf, resolution 1.80Å

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