2f78: Difference between revisions

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==BenM effector binding domain with its effector benzoate==
==BenM effector binding domain with its effector benzoate==
<StructureSection load='2f78' size='340' side='right' caption='[[2f78]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='2f78' size='340' side='right'caption='[[2f78]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f78]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Acibi Acibi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F78 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2F78 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f78]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baylyi Acinetobacter baylyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F78 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f6g|2f6g]], [[2f6p|2f6p]], [[2f7a|2f7a]], [[2f7b|2f7b]], [[2f7c|2f7c]], [[2f8d|2f8d]], [[2f97|2f97]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">benM, benR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=202950 ACIBI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f78 OCA], [https://pdbe.org/2f78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f78 RCSB], [https://www.ebi.ac.uk/pdbsum/2f78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f78 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f78 OCA], [http://pdbe.org/2f78 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2f78 RCSB], [http://www.ebi.ac.uk/pdbsum/2f78 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2f78 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BENM_ACIAD BENM_ACIAD]] Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes, which can be regulated by CatM. Binds to the inducers cis,cis-muconate and benzoate.  
[https://www.uniprot.org/uniprot/BENM_ACIAD BENM_ACIAD] Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes, which can be regulated by CatM. Binds to the inducers cis,cis-muconate and benzoate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f78_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f7/2f78_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2f78" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2f78" style="background-color:#fffaf0;"></div>
==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acibi]]
[[Category: Acinetobacter baylyi]]
[[Category: Clark, T]]
[[Category: Large Structures]]
[[Category: Ezezika, O]]
[[Category: Clark T]]
[[Category: Haddad, S]]
[[Category: Ezezika O]]
[[Category: Momany, C]]
[[Category: Haddad S]]
[[Category: Neidle, E]]
[[Category: Momany C]]
[[Category: Effector binding domain]]
[[Category: Neidle E]]
[[Category: Gene regulation]]
[[Category: Inducer binding domain]]
[[Category: Lttr]]
[[Category: Lysr-type transcriptional regulator]]
Retrieved from "https://proteopedia.org/2f78"