2gf9: Difference between revisions

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==Crystal structure of human RAB3D in complex with GDP==
==Crystal structure of human RAB3D in complex with GDP==
<StructureSection load='2gf9' size='340' side='right' caption='[[2gf9]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
<StructureSection load='2gf9' size='340' side='right'caption='[[2gf9]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gf9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gf9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GF9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAB3D, GOV, RAB16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf9 OCA], [http://pdbe.org/2gf9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gf9 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf9 OCA], [https://pdbe.org/2gf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gf9 RCSB], [https://www.ebi.ac.uk/pdbsum/2gf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gf9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RAB3D_HUMAN RAB3D_HUMAN]] Protein transport. Probably involved in regulated exocytosis (By similarity).  
[https://www.uniprot.org/uniprot/RAB3D_HUMAN RAB3D_HUMAN] Protein transport. Probably involved in regulated exocytosis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 20: Line 20:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf9 ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gf9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bochkarev, A]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M]]
[[Category: Bochkarev A]]
[[Category: Hong, B]]
[[Category: Edwards AM]]
[[Category: Landry, R]]
[[Category: Hong B]]
[[Category: Park, H]]
[[Category: Landry R]]
[[Category: Structural genomic]]
[[Category: Park H]]
[[Category: Shen, L]]
[[Category: Shen L]]
[[Category: Sundstrom, M]]
[[Category: Sundstrom M]]
[[Category: Tempel, W]]
[[Category: Tempel W]]
[[Category: Wang, J]]
[[Category: Wang J]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: G-protein]]
[[Category: Protein transport]]
[[Category: Rab]]
[[Category: Sgc]]
Retrieved from "https://proteopedia.org/2gf9"