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==Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant==
==Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant==
<StructureSection load='2nrn' size='340' side='right' caption='[[2nrn]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='2nrn' size='340' side='right'caption='[[2nrn]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nrn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NRN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nrn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NRN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zta|2zta]], [[2b1f|2b1f]], [[2hy6|2hy6]], [[2b22|2b22]], [[2ipz|2ipz]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCN4, AAS3, ARG9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrn OCA], [https://pdbe.org/2nrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nrn RCSB], [https://www.ebi.ac.uk/pdbsum/2nrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrn OCA], [http://pdbe.org/2nrn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nrn RCSB], [http://www.ebi.ac.uk/pdbsum/2nrn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.  
[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 2nrn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2nrn" style="background-color:#fffaf0;"></div>
==See Also==
*[[Gcn4 3D Structures|Gcn4 3D Structures]]
*[[Gnc4 3D Structures|Gnc4 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Liu, J]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Lu, M]]
[[Category: Liu J]]
[[Category: Biosynthetic protein]]
[[Category: Lu M]]
[[Category: Coiled coil]]
[[Category: Protein design]]
[[Category: Protein structure]]
[[Category: Tetramer]]

Latest revision as of 13:09, 26 July 2023

Self-assembly of coiled-coil tetramers in the 1.40 A structure of a leucine-zipper mutant

2nrn, resolution 1.40Å

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