Core-binding factor: Difference between revisions
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<StructureSection load=' | <StructureSection load='' size='340' side='right' caption='Human CBFα runt domain (magenta) complex with CBFβ heterodimerization domain (green) and DNA (PDB code [[1h9d]])' scene='70/708082/Cv/1'> | ||
== Function == | == Function == | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*Core-binding factor α subunit | *Core-binding factor α subunit | ||
**[[1ean]], [[1ljm]] – hCBFα runt domain - human<br /> | **[[1ean]], [[1ljm]] – hCBFα runt domain - human<br /> | ||
**[[1cmo]], [[2n7b]] – hCBFα runt domain (mutant) - NMR<br /> | **[[1cmo]], [[2n7b]] – hCBFα runt domain (mutant) - NMR<br /> | ||
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**[[1hjb]] – mCBFα runt domain + hEBP β + DNA<br /> | **[[1hjb]] – mCBFα runt domain + hEBP β + DNA<br /> | ||
**[[4l0y]], [[4l0z]], [[4l18]], [[3wu1]] – mCBFα runt domain + hETS1 + DNA<br /> | **[[4l0y]], [[4l0z]], [[4l18]], [[3wu1]] – mCBFα runt domain + hETS1 + DNA<br /> | ||
*Core-binding factor β subunit | *Core-binding factor β subunit | ||
**[[4n9f]] – hCBFb + cullin-5 + elongin-B + virion infectivity factor<br /> | |||
**[[6p59]] – hCBFb + elongin-B + elongin-C + virion infectivity factor<br /> | |||
**[[6nil]] – hCBFb + A3F complex + virion infectivity factor – Cryo EM<br /> | |||
**[[8e40]], [[8h0i]], [[8j62]] – hCBFb + APOBEC + virion infectivity factor + RNA – Cryo EM<br /> | |||
**[[8cx0]], [[8cx1]], [[8cx2]] – hCBFb + elongin-B + elongin-C + APOBEC + virion infectivity factor + RNA – Cryo EM<br /> | |||
**[[8fvi]] – hCBFb + APOBEC + virion infectivity factor + cullin 5 + RNA – Cryo EM<br /> | |||
**[[8fvj]] – hCBFb + elongin-B + elongin-C + virion infectivity factor + cullin 5 – Cryo EM<br /> | |||
**[[8szk]] – hCBFb + elongin-B + elongin-C + virion infectivity factor + cullin 5 + RNA – Cryo EM<br /> | |||
**[[6vg2]], [[6vg8]], [[6vgd]], [[6vge]], [[6vgg]] – hCBFb + Runx2 + FLI1 + DNA<br /> | |||
**[[1ilf]] – mCBFb<br /> | **[[1ilf]] – mCBFb<br /> | ||
*Core-binding factor α+β subunits | *Core-binding factor α+β subunits | ||
**[[1e50]] – hCBFα runt domain + hCBFβ heterodimerization domain<br /> | **[[1e50]] – hCBFα runt domain + hCBFβ heterodimerization domain<br /> | ||
**[[1h9d]] – hCBFα runt domain + hCBFβ heterodimerization domain + DNA<br /> | **[[1h9d]] – hCBFα runt domain + hCBFβ heterodimerization domain + DNA<br /> | ||
