3e9f: Difference between revisions

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==Crystal structure short-form (residue1-113) of Eaf3 chromo domain==
==Crystal structure short-form (residue1-113) of Eaf3 chromo domain==
<StructureSection load='3e9f' size='340' side='right' caption='[[3e9f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3e9f' size='340' side='right'caption='[[3e9f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3e9f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3E9F FirstGlance]. <br>
<table><tr><td colspan='2'>[[3e9f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E9F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e9g|3e9g]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3e9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9f OCA], [http://pdbe.org/3e9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3e9f RCSB], [http://www.ebi.ac.uk/pdbsum/3e9f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e9f OCA], [https://pdbe.org/3e9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e9f RCSB], [https://www.ebi.ac.uk/pdbsum/3e9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e9f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EAF3_YEAST EAF3_YEAST]] Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.<ref>PMID:11036083</ref> <ref>PMID:14701747</ref> <ref>PMID:15045029</ref>
[https://www.uniprot.org/uniprot/EAF3_YEAST EAF3_YEAST] Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.<ref>PMID:11036083</ref> <ref>PMID:14701747</ref> <ref>PMID:15045029</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/3e9f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e9/3e9f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Ding, J]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Hong, J]]
[[Category: Ding J]]
[[Category: Lin, D]]
[[Category: Hong J]]
[[Category: Sun, B]]
[[Category: Lin D]]
[[Category: Zhang, P]]
[[Category: Sun B]]
[[Category: Chromatin regulator]]
[[Category: Zhang P]]
[[Category: Chromatin remodeling]]
[[Category: Chromo domain]]
[[Category: Dna damage]]
[[Category: Dna repair]]
[[Category: Eaf3]]
[[Category: Nucleus]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription regulation]]
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