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==Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)==
==Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)==
<StructureSection load='5ud5' size='340' side='right' caption='[[5ud5]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='5ud5' size='340' side='right'caption='[[5ud5]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ud5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UD5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UD5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ud5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei_Go1 Methanosarcina mazei Go1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UD5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.347&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyrrolysine--tRNA(Pyl)_ligase Pyrrolysine--tRNA(Pyl) ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.26 6.1.1.26] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ud5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ud5 OCA], [http://pdbe.org/5ud5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ud5 RCSB], [http://www.ebi.ac.uk/pdbsum/5ud5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ud5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ud5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ud5 OCA], [https://pdbe.org/5ud5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ud5 RCSB], [https://www.ebi.ac.uk/pdbsum/5ud5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ud5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA]] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).  
[https://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).
 
==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Soll, D]]
[[Category: Large Structures]]
[[Category: Suzuki, T]]
[[Category: Methanosarcina mazei Go1]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Soll D]]
[[Category: Ligase-rna complex]]
[[Category: Suzuki T]]
[[Category: Pylr]]
[[Category: Trna]]

Latest revision as of 14:26, 6 March 2024

Crystal structure of the tRNA binding domain of Pyrrolysyl-tRNA synthetase bound to tRNA(Pyl)

5ud5, resolution 2.35Å

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