1mtx: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:


==DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF MARGATOXIN BY 1H, 13C, 15N TRIPLE-RESONANCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY==
==DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF MARGATOXIN BY 1H, 13C, 15N TRIPLE-RESONANCE NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY==
<StructureSection load='1mtx' size='340' side='right' caption='[[1mtx]], [[NMR_Ensembles_of_Models | 23 NMR models]]' scene=''>
<StructureSection load='1mtx' size='340' side='right'caption='[[1mtx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mtx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Centruroides_margaritatus Centruroides margaritatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MTX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mtx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Centruroides_margaritatus Centruroides margaritatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MTX FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mtx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mtx OCA], [http://pdbe.org/1mtx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mtx RCSB], [http://www.ebi.ac.uk/pdbsum/1mtx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1mtx ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 23 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mtx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mtx OCA], [https://pdbe.org/1mtx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mtx RCSB], [https://www.ebi.ac.uk/pdbsum/1mtx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mtx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KAX22_CENMA KAX22_CENMA]] Potent selective inhibitor of voltage-dependent potassium channels such as Kv1.3/KCNA3.<ref>PMID:8360176</ref>
[https://www.uniprot.org/uniprot/KAX22_CENMA KAX22_CENMA] Potent selective inhibitor of voltage-dependent potassium channels such as Kv1.3/KCNA3.<ref>PMID:8360176</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/1mtx_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/1mtx_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
Line 27: Line 28:
</div>
</div>
<div class="pdbe-citations 1mtx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1mtx" style="background-color:#fffaf0;"></div>
==See Also==
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 32: Line 36:
</StructureSection>
</StructureSection>
[[Category: Centruroides margaritatus]]
[[Category: Centruroides margaritatus]]
[[Category: Johnson, B A]]
[[Category: Large Structures]]
[[Category: Stevens, S P]]
[[Category: Johnson BA]]
[[Category: Williamson, J M]]
[[Category: Stevens SP]]
[[Category: Toxin]]
[[Category: Williamson JM]]
Retrieved from "https://proteopedia.org/1mtx"