6et5: Difference between revisions
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New page: '''Unreleased structure''' The entry 6et5 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==Reaction centre light harvesting complex 1 from Blc. virids== | ||
<SX load='6et5' size='340' side='right' viewer='molstar' caption='[[6et5]], [[Resolution|resolution]] 2.87Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6et5]] is a 54 chain structure with sequence from [https://en.wikipedia.org/wiki/Blastochloris_viridis Blastochloris viridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ET5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ET5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.87Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BPB:BACTERIOPHEOPHYTIN+B'>BPB</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FME:N-FORMYLMETHIONINE'>FME</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MQ9:MENAQUINONE-9'>MQ9</scene>, <scene name='pdbligand=NS0:(6~{E},10~{E},12~{E},14~{E},16~{E},18~{E},20~{E},22~{E},26~{E})-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26-undecaene'>NS0</scene>, <scene name='pdbligand=NS5:15-CIS-1,2-DIHYDRONEUROSPORENE'>NS5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UQ9:UBIQUINONE-9'>UQ9</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6et5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6et5 OCA], [https://pdbe.org/6et5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6et5 RCSB], [https://www.ebi.ac.uk/pdbsum/6et5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6et5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CYCR_BLAVI CYCR_BLAVI] The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.<ref>PMID:10736158</ref> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The light-harvesting 1-reaction centre (LH1-RC) complex is a key functional component of bacterial photosynthesis. Here we present a 2.9 A resolution cryo-electron microscopy structure of the bacteriochlorophyll b-based LH1-RC complex from Blastochloris viridis that reveals the structural basis for absorption of infrared light and the molecular mechanism of quinone migration across the LH1 complex. The triple-ring LH1 complex comprises a circular array of 17 beta-polypeptides sandwiched between 17 alpha- and 16 gamma-polypeptides. Tight packing of the gamma-apoproteins between beta-polypeptides collectively interlocks and stabilizes the LH1 structure; this, together with the short Mg-Mg distances of bacteriochlorophyll b pairs, contributes to the large redshift of bacteriochlorophyll b absorption. The 'missing' 17th gamma-polypeptide creates a pore in the LH1 ring, and an adjacent binding pocket provides a folding template for a quinone, Q P, which adopts a compact, export-ready conformation before passage through the pore and eventual diffusion to the cytochrome bc 1 complex. | |||
Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 A.,Qian P, Siebert CA, Wang P, Canniffe DP, Hunter CN Nature. 2018 Apr;556(7700):203-208. doi: 10.1038/s41586-018-0014-5. Epub 2018 Apr, 4. PMID:29618818<ref>PMID:29618818</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
<div class="pdbe-citations 6et5" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Blastochloris viridis]] | |||
[[Category: Large Structures]] | |||
[[Category: Canniffe DP]] | |||
[[Category: Hunter CN]] | |||
[[Category: Qian P]] | |||
[[Category: Siebert CA]] | |||
[[Category: Wang P]] | |||
Latest revision as of 09:00, 9 April 2025
Reaction centre light harvesting complex 1 from Blc. virids
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