1zkh: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (11 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Solution structure of a human ubiquitin-like domain in SF3A1== | |||
<StructureSection load='1zkh' size='340' side='right'caption='[[1zkh]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1zkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZKH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zkh OCA], [https://pdbe.org/1zkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zkh RCSB], [https://www.ebi.ac.uk/pdbsum/1zkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zkh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
'' | Check<jmol> | ||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/1zkh_consurf.spt"</scriptWhenChecked> | |||
== | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zkh ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Avvakumov | [[Category: Avvakumov GV]] | ||
[[Category: Dhe-Paganon | [[Category: Dhe-Paganon S]] | ||
[[Category: Edwards | [[Category: Edwards A]] | ||
[[Category: Guido | [[Category: Guido V]] | ||
[[Category: Lemak | [[Category: Lemak A]] | ||
[[Category: Lukin | [[Category: Lukin JA]] | ||
[[Category: Mackenzie | [[Category: Mackenzie F]] | ||
[[Category: Newman | [[Category: Newman EM]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | [[Category: Xue S]] | ||
[[Category: Xue | |||
Latest revision as of 08:11, 15 May 2024
Solution structure of a human ubiquitin-like domain in SF3A1
| ||||||||||||
