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==Crystal Structure of Human Carbonic Anhydrase vi==
==Crystal Structure of Human Carbonic Anhydrase vi==
<StructureSection load='3fe4' size='340' side='right' caption='[[3fe4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3fe4' size='340' side='right'caption='[[3fe4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fe4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FE4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fe4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FE4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fe4 OCA], [https://pdbe.org/3fe4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fe4 RCSB], [https://www.ebi.ac.uk/pdbsum/3fe4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fe4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fe4 OCA], [http://pdbe.org/3fe4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fe4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fe4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fe4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CAH6_HUMAN CAH6_HUMAN]] Reversible hydration of carbon dioxide. Its role in saliva is unknown.  
[https://www.uniprot.org/uniprot/CAH6_HUMAN CAH6_HUMAN] Reversible hydration of carbon dioxide. Its role in saliva is unknown.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3fe4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3fe4" style="background-color:#fffaf0;"></div>
==See Also==
*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Delft, F von]]
[[Category: Edwards A]]
[[Category: Edwards, A]]
[[Category: Kochan G]]
[[Category: Kochan, G]]
[[Category: Krysztofinska E]]
[[Category: Krysztofinska, E]]
[[Category: Muniz J]]
[[Category: Muniz, J]]
[[Category: Oppermann U]]
[[Category: Oppermann, U]]
[[Category: Pilka ES]]
[[Category: Pilka, E S]]
[[Category: Roos AK]]
[[Category: Roos, A K]]
[[Category: Weigelt J]]
[[Category: Structural genomic]]
[[Category: Yue WW]]
[[Category: Weigelt, J]]
[[Category: Von Delft F]]
[[Category: Yue, W W]]
[[Category: Carbonic anhydrase]]
[[Category: Glycoprotein]]
[[Category: Lyase]]
[[Category: Metal binding]]
[[Category: Metal-binding]]
[[Category: Secreted]]
[[Category: Secretion]]
[[Category: Sgc]]

Latest revision as of 15:29, 1 November 2023

Crystal Structure of Human Carbonic Anhydrase vi

3fe4, resolution 1.90Å

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