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==Structure of the human SRP68-RBD==
==Structure of the human SRP68-RBD==
<StructureSection load='4p3f' size='340' side='right' caption='[[4p3f]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4p3f' size='340' side='right'caption='[[4p3f]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4p3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P3F FirstGlance]. <br>
<table><tr><td colspan='2'>[[4p3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P3F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.699&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p3g|4p3g]], [[4p3e|4p3e]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SRP68 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3f OCA], [https://pdbe.org/4p3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p3f RCSB], [https://www.ebi.ac.uk/pdbsum/4p3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p3f ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p3f OCA], [http://pdbe.org/4p3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p3f RCSB], [http://www.ebi.ac.uk/pdbsum/4p3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p3f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SRP68_HUMAN SRP68_HUMAN]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.  
[https://www.uniprot.org/uniprot/SRP68_HUMAN SRP68_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4p3f" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4p3f" style="background-color:#fffaf0;"></div>
==See Also==
*[[Signal recognition particle protein|Signal recognition particle protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Grotwinkel, J T]]
[[Category: Large Structures]]
[[Category: Sinning, I]]
[[Category: Grotwinkel JT]]
[[Category: Wild, K]]
[[Category: Sinning I]]
[[Category: Rna binding protein]]
[[Category: Wild K]]
Retrieved from "https://proteopedia.org/4p3f"