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[[Image:295d.jpg|left|200px]]


{{Structure
==CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY==
|PDB= 295d |SIZE=350|CAPTION= <scene name='initialview01'>295d</scene>, resolution 1.500&Aring;
<StructureSection load='295d' size='340' side='right'caption='[[295d]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
<table><tr><td colspan='2'>[[295d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=295D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=295D FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=295d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=295d OCA], [https://pdbe.org/295d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=295d RCSB], [https://www.ebi.ac.uk/pdbsum/295d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=295d ProSAT]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
__TOC__
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=295d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=295d OCA], [http://www.ebi.ac.uk/pdbsum/295d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=295d RCSB]</span>
</StructureSection>
}}
[[Category: Large Structures]]
 
[[Category: Brown DG]]
'''CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY'''
[[Category: Chwalinski T]]
 
[[Category: Clark GR]]
 
[[Category: Garman E]]
==Overview==
[[Category: Jones RL]]
A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed.
[[Category: Neidle S]]
 
[[Category: Sanderson MR]]
==About this Structure==
[[Category: Stuart DI]]
295D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=295D OCA].
[[Category: Veal JM]]
 
[[Category: Wilson WD]]
==Reference==
[[Category: Zon G]]
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2216724 2216724]
[[Category: Protein complex]]
[[Category: Brown, D G.]]
[[Category: Chwalinski, T.]]
[[Category: Clark, G R.]]
[[Category: Garman, E.]]
[[Category: Jones, R L.]]
[[Category: Neidle, S.]]
[[Category: Sanderson, M R.]]
[[Category: Stuart, D I.]]
[[Category: Veal, J M.]]
[[Category: Wilson, W D.]]
[[Category: Zon, G.]]
[[Category: a-dna]]
[[Category: double helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:02 2008''

Latest revision as of 09:10, 14 February 2024

CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY

295d, resolution 1.50Å

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